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» Home : Publication : J Herpe Med Surg : J Herpe Med Surg Spring'04 Vol. 14 No. 1 |
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J Herpe Med Surg
Severe Melanomacrophage Hyperplasia in a Lizard, Shinisaurus crocodilurus: A Review of Melanomacrophages in Ectotherms * Zoltan S. Gyimesi, DVM and Elizabeth W. Howerth, DVM, PhD, DACVP
* Louisville Zoological Garden, 1100 Trevilian Way, PO Box 37250, Louisville, KY 40233, USA; Department of Veterinary Pathology, College of Veterinary Medicine The University of Georgia, Athens, GA 30602, USA An adult male crocodile lizard, Shinisaurus crocodilurus, presented lethargic and cachexic and died three days later. Gross necropsy revealed a darkly pigmented liver and spleen. Histopathologic examination revealed severe, disseminated melanomacrophage hyperplasia confirmed by special staining and electron microscopy. The definitive etiology is unclear, but the time of year and the lizard's age and nutritional state are predisposing factors. The degree of hepatic melanomacrophage hyperplasia is believed to have impaired liver function and is suspected to have been a significant contributor to the morbidity and mortality in this case. The incidence and roles of melanomacrophages in ectotherms are reviewed. [Abstract] Address (URL): http://www.arav.org/journals/JA021861.htm
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 J Herpe Med Surg Spring'04 Vol. 14 No. 1 |
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